Errata: Time-reversed ultrasonically encoded optical focusing in biological tissue

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Time-reversed ultrasonically encoded optical focusing in biological tissue.

We report an experimental investigation of time-reversed ultrasonically encoded optical focusing in biological tissue. This technology combines the concepts of optical phase conjugation and ultrasound modulation of diffused coherent light. The ultrasonically encoded (or tagged) diffused light from a tissue sample is collected in reflection mode and interferes with a reference light in a photore...

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Frequency-swept time-reversed ultrasonically encoded optical focusing.

A technique to rapidly scan an optical focus inside a turbid medium is attractive for various biomedical applications. Time-reversed ultrasonically encoded (TRUE) optical focusing has previously demonstrated light focusing into a turbid medium, using both analog and digital devices. Although the digital implementation can generate a focus with high energy, it has been time consuming to scan the...

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Time-reversed ultrasonically encoded optical focusing into scattering media

Light focusing plays a central role in biomedical imaging, manipulation, and therapy. In scattering media, direct light focusing becomes infeasible beyond one transport mean free path. All previous methods1-3 to overcome this diffusion limit lack a practical internal "guide star."4 Here we proposed and experimentally validated a novel concept, called Time-Reversed Ultrasonically Encoded (TRUE) ...

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Deep tissue optical focusing and optogenetic modulation with time-reversed ultrasonically encoded light

Noninvasive light focusing deep inside living biological tissue has long been a goal in biomedical optics. However, the optical scattering of biological tissue prevents conventional optical systems from tightly focusing visible light beyond several hundred micrometers. The recently developed wavefront shaping technique time-reversed ultrasonically encoded (TRUE) focusing enables noninvasive lig...

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Iterative Time-Reversed Ultrasonically Encoded Light Focusing in Backscattering Mode

The Time-Reversed Ultrasound-Encoded (TRUE) light technique enables noninvasive focusing deep inside scattering media. However, the time-reversal procedure usually has a low signal-to-noise ratio because the intensity of ultrasound-encoded light is intrinsically low. Consequently, the contrast and resolution of TRUE focus is far from ideal, especially in the backscattering geometry, which is mo...

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ژورنال

عنوان ژورنال: Journal of Biomedical Optics

سال: 2012

ISSN: 1083-3668

DOI: 10.1117/1.jbo.17.4.049802